ELISA Kit for Pig Selenoprotein S

Mfr.No.	E10141p
Alternative Names	SELS
Categories	Elisa
Function	Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination.
Specificity	Natural and recombinant Pig Selenoprotein S
Subcellular Location	Cytoplasm Endoplasmic reticulum membrane Single-pass membrane protein
Detection Range	0.156-10ng/ml
Entryname	SELS_PIG
Method Type	Sandwich
Platform	PF06936
Protein Name	Selenoprotein S
Sensitivity	0.05ng/ml
Sequence	50: MEQDGDQLSA ; RPALETEGLR ; FLHVTVGSLL ; ATYGWYIVFC ; CILLYVVFQK ; 100: LSTRLRALRQ ; RHLDGAAAAL ; EPDVVVKRQE ; ALAAARLKMQ ; EELNAQVEKH ; 150: KEKLRQLEEE ; KRRQKIERWD ; SVQEGRSYRG ; DARKRQEEDS ; PGPSTSSVIP ; 190: KRKSDKKPLR ; GGGYNPLSGE ; GGGACSWRPG ; RRGPSSGGUG ;
Sequence Length	190
Sub Unit	Interacts with DERL1 and VCP, suggesting that it forms a membrane complex with DERL1 that serves as a receptor for VCP.

Reference	1. "Molecular characterization and NF-kappaB-regulated transcription of selenoprotein S from the Bama mini-pig." Zhang N., Jing W., Cheng J., Cui W., Mu Y., Li K., Lei X. Mol. Biol. Rep.38:4281-4286(2011) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;TISSUE SPECIFICITY strain: Guanxi bama miniature pig. tissue: Liver. 2. Swine Genome Sequencing Consortium. Submitted (2009-11) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] strain: Landrace.

Have you used this product?

SKU	Supplier No.	Size	Your price	Quantity
BHE13810376	E10141p	96T	$900		Add to Cart