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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Presenilin-2

SKU : BHE13809155

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1274m
Alternative Names	Ad4h ; Alg3 ; Ps-2 ; Psnl2
Categories	Elisa
Function	Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins.
Specificity	Natural and recombinant Mouse Presenilin-2
Subcellular Location	Endoplasmic reticulum membrane Multi-pass membrane protein Golgi apparatus membrane Multi-pass membrane protein
Detection Range	31.2-2000pg/mL
Entryname	PSN2_MOUSE
Method Type	Sandwich
Platform	PF01080
Protein Name	Presenilin-2
Sensitivity	15.66pg/mL
Sequence	50: MLAFMASDSE ; EEVCDERTSL ; MSAESPTSRS ; CQEGRPGPED ; GESTAQWRTQ ; 100: ESEEDCEEDP ; DRYACSGAPG ; RPSGLEEELT ; LKYGAKRVIM ; LFVPVTLCMI ; 150: VVVATIKSVR ; FYTEKNGQLI ; YTPFTEDTPS ; VGQRLLNSVL ; NTLIMISVIV ; 200: VMTIFLVVLY ; KYRCYKFIHG ; WLIMSSLMLL ; FLFTYIYLGE ; VLKTYNVAMD ; 250: YPTLFLAVWN ; FGAVGMVCIH ; WKGPLVLQQA ; YLIVISALMA ; LVFIKYLPEW ; 300: SAWVILGAIS ; VYDLVAVLCP ; KGPLRMLVET ; AQERNEPIFP ; ALIYSSAMVW ; 350: TVGMAKLDPS ; SQGALQLPYD ; PEMEEDSYDS ; FGEPSYPEAF ; EAPLPGYPGE ; 400: ELEEEEERGV ; KLGLGDFIFY ; SVLVGKAAAT ; GNGDWNTTLA ; CFIAILIGLC ; 448: LTLLLLAVFK ; KALPALPISI ; TFGLIFYFST ; DNLVRPFMDT ; LASHQLYI
Sequence Length	448
String	Q61144
Sub Unit	Homodimer. Component of the gamma-secretase complex, a complex composed of a presenilin homodimer (PSEN1 or PSEN2), nicastrin (NCSTN), APH1 (APH1A or APH1B) and PEN2. Such minimal complex is sufficient for secretase activity, although other components may exist. Interacts with DOCK3. Interacts with HERPUD1, FLNA, FLNB and PARL.

Uniprot	Q61144
Gene Name	Psen2
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:19165
Unigene	Mm.330850

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809155	E1274m	96T	$776		Add to Cart

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