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ELISA Kit for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2

SKU : BHE13805358

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E15069m
Alternative Names	Brain cyclic nucleotide-gated channel 2 ; BCNG-2 ; Hyperpolarization-activated cation channel 1 ; HAC-1 ; Bcng2 ; Hac1
Categories	Elisa
Function	Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). Produces a large instantaneous current. Activated by cAMP. Modulated by intracellular chloride ions and pH; acidic pH shifts the activation to more negative voltages.
Specificity	Natural and recombinant Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Subcellular Location	Membrane Multi-pass membrane protein
Detection Range	0.312-20ng/mL
Entryname	HCN2_MOUSE
Method Type	Sandwich
Platform	PF00027
Protein Name	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Sensitivity	0.172ng/mL
Sequence	50: MDARGGGGRP ; GDSPGTTPAP ; GPPPPPPPPA ; PPQPQPPPAP ; PPNPTTPSHP ; 100: ESADEPGPRA ; RLCSRDSACT ; PGAAKGGANG ; ECGRGEPQCS ; PEGPARGPKV ; 150: SFSCRGAASG ; PSAAEEAGSE ; EAGPAGEPRG ; SQASFLQRQF ; GALLQPGVNK ; 200: FSLRMFGSQK ; AVEREQERVK ; SAGAWIIHPY ; SDFRFYWDFT ; MLLFMVGNLI ; 250: IIPVGITFFK ; DETTAPWIVF ; NVVSDTFFLM ; DLVLNFRTGI ; VIEDNTEIIL ; 300: DPEKIKKKYL ; RTWFVVDFVS ; SIPVDYIFLI ; VEKGIDSEVY ; KTARALRIVR ; 350: FTKILSLLRL ; LRLSRLIRYI ; HQWEEIFHMT ; YDLASAVMRI ; CNLISMMLLL ; 400: CHWDGCLQFL ; VPMLQDFPSD ; CWVSINNMVN ; HSWSELYSFA ; LFKAMSHMLC ; 450: IGYGRQAPES ; MTDIWLTMLS ; MIVGATCYAM ; FIGHATALIQ ; SLDSSRRQYQ ; 500: EKYKQVEQYM ; SFHKLPADFR ; QKIHDYYEHR ; YQGKMFDEDS ; ILGELNGPLR ; 550: EEIVNFNCRK ; LVASMPLFAN ; ADPNFVTAML ; TKLKFEVFQP ; GDYIIREGTI ; 600: GKKMYFIQHG ; VVSVLTKGNK ; EMKLSDGSYF ; GEICLLTRGR ; RTASVRADTY ; 650: CRLYSLSVDN ; FNEVLEEYPM ; MRRAFETVAI ; DRLDRIGKKN ; SILLHKVQHD ; 700: LSSGVFNNQE ; NAIIQEIVKY ; DREMVQQAEL ; GQRVGLFPPP ; PPPQVTSAIA ; 750: TLQQAVAMSF ; CPQVARPLVG ; PLALGSPRLV ; RRAPPGPLPP ; AASPGPPAAS ; 800: PPAAPSSPRA ; PRTSPYGVPG ; SPATRVGPAL ; PARRLSRASR ; PLSASQPSLP ; 850: HGVPAPSPAA ; SARPASSSTP ; RLGPAPTART ; AAPSPDRRDS ; ASPGAASGLD ; 863: PLDSARSRLS ; SNL
Sequence Length	863
String	O88703
Sub Unit	The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming subunits. Heteromultimer with HCN1. Interacts with KCNE2.

Uniprot	O88703
Gene Name	Hcn2
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:15166
Unigene	Mm.12956

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805358	E15069m	96T	$776		Add to Cart

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