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ELISA Kit for Mouse Hepatocyte growth factor

SKU : BHE13805200

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0047m
Alternative Names	Hepatopoietin-A ; Scatter factor ; SF
Categories	Elisa
Function	HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as growth factor for a broad spectrum of tissues and cell types. It has no detectable protease activity.
Specificity	Natural and recombinant Mouse Hepatocyte growth factor
Detection Range	0.156-10ng/mL
Entryname	HGF_MOUSE
Method Type	Sandwich
Platform	PF00051
Protein Name	Hepatocyte growth factor
Sensitivity	0.078ng/mL
Sequence	50: MMWGTKLLPV ; LLLQHVLLHL ; LLLHVAIPYA ; EGQKKRRNTL ; HEFKKSAKTT ; 100: LTKEDPLLKI ; KTKKVNSADE ; CANRCIRNRG ; FTFTCKAFVF ; DKSRKRCYWY ; 150: PFNSMSSGVK ; KGFGHEFDLY ; ENKDYIRNCI ; IGKGGSYKGT ; VSITKSGIKC ; 200: QPWNSMIPHE ; HSFLPSSYRG ; KDLQENYCRN ; PRGEEGGPWC ; FTSNPEVRYE ; 250: VCDIPQCSEV ; ECMTCNGESY ; RGPMDHTESG ; KTCQRWDQQT ; PHRHKFLPER ; 300: YPDKGFDDNY ; CRNPDGKPRP ; WCYTLDPDTP ; WEYCAIKTCA ; HSAVNETDVP ; 350: METTECIQGQ ; GEGYRGTSNT ; IWNGIPCQRW ; DSQYPHKHDI ; TPENFKCKDL ; 400: RENYCRNPDG ; AESPWCFTTD ; PNIRVGYCSQ ; IPKCDVSSGQ ; DCYRGNGKNY ; 450: MGNLSKTRSG ; LTCSMWDKNM ; EDLHRHIFWE ; PDASKLNKNY ; CRNPDDDAHG ; 500: PWCYTGNPLI ; PWDYCPISRC ; EGDTTPTIVN ; LDHPVISCAK ; TKQLRVVNGI ; 550: PTQTTVGWMV ; SLKYRNKHIC ; GGSLIKESWV ; LTARQCFPAR ; NKDLKDYEAW ; 600: LGIHDVHERG ; EEKRKQILNI ; SQLVYGPEGS ; DLVLLKLARP ; AILDNFVSTI ; 650: DLPSYGCTIP ; EKTTCSIYGW ; GYTGLINADG ; LLRVAHLYIM ; GNEKCSQHHQ ; 700: GKVTLNESEL ; CAGAEKIGSG ; PCEGDYGGPL ; ICEQHKMRMV ; LGVIVPGRGC ; 728: AIPNRPGIFV ; RVAYYAKWIH ; KVILTYKL
Sequence Length	728
String	Q08048
Sub Unit	Dimer of an alpha chain and a beta chain linked by a disulfide bond.

Uniprot	Q08048
Gene Name	Hgf
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:15234
Unigene	Mm.267078

Reference	1. "Identification of mouse mammary fibroblast-derived mammary growth factor as hepatocyte growth factor." Sasaki M., Nishio M., Sasaki T., Enami J. Biochem. Biophys. Res. Commun.199:772-779(1994) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS LONG AND SHORT);PROTEIN SEQUENCE OF 496-504 tissue: Mammary fibroblast. 2. "Structure, genetic mapping, and expression of the mouse Hgf/scatter factor gene." Lee C.C., Kozak C.A., Yamada K.M. Cell Adhes. Commun.1:101-111(1993) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Liver. 3. "Molecular cloning and characterization of cDNA encoding mouse hepatocyte growth factor." Liu Y., Michalopoulos G.K., Zarnegar R. Biochim. Biophys. Acta1216:299-303(1993) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Liver. 4. "NK1, a natural splice variant of hepatocyte growth factor/scatter factor, is a partial agonist in vivo." Jakubczak J.L., LaRochelle W.J., Merlino G. Mol. Cell. Biol.18:1275-1283(1998) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM NK1) tissue: Lung. 5. Sharpe M.J.S., Lane K., Gherardi E. Submitted (1999-01) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LONG) strain: Swiss. tissue: Fibroblast. 6. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C. Submitted (2005-09) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] 7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM LONG) tissue: Brain. 8. "Characterisation of the scatter factor/hepatocyte growth factor gene promoter: positive and negative regulatory elements direct gene expression to mesenchymal cells." Plaschke-Schluetter A., Behrens J., Gherardi E., Birchmeier W. J. Biol. Chem.270:830-836(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-30 strain: 129. 9. "Purified scatter factor stimulates epithelial and vascular endothelial cell migration." Rosen E.M., Meromsky L., Setter E., Vinter D.W., Goldberg I.D. Proc. Soc. Exp. Biol. Med.195:34-43(1990) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 184-197; 357-367; 375-383 AND 653-666 10. "Hepatocytes and scatter factor." Gherardi E., Stoker M. Nature346:228-228(1990) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 496-519 11. "Purification and characterization of biologically active scatter factor from ras-transformed NIH 3T3 conditioned medium." Coffer A., Fellows J., Young S., Pappin D., Rahman D. Biochem. J.278:35-41(1991) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 496-519 12. "A mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist." Tolbert W.D., Daugherty J., Gao C., Xie Q., Miranti C., Gherardi E., Woude G.V., Xu H.E. Proc. Natl. Acad. Sci. U.S.A.104:14592-14597(2007) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 29-210;DISULFIDE BONDS 13. "Structural basis for agonism and antagonism of hepatocyte growth factor." Tolbert W.D., Daugherty-Holtrop J., Gherardi E., Vande Woude G., Xu H.E. Proc. Natl. Acad. Sci. U.S.A.107:13264-13269(2010) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 31-127;DISULFIDE BONDS;FUNCTION

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