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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Cold-inducible RNA-binding protein

SKU : BHE13802085

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E12931m
Alternative Names	A18 hnRNP ; Glycine-rich RNA-binding protein CIRP ; Cirp
Categories	Elisa
Function	Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Promotes assembly of stress granules (SGs), when overexpressed. Seems to play an essential role in cold-induced suppression of cell proliferation. Acts as a translational repressor. Acts as a translational activator. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN.
Specificity	Natural and recombinant Mouse Cold-inducible RNA-binding protein
Subcellular Location	Nucleus nucleoplasm Cytoplasm Translocates from the nucleus to the cytoplasm after exposure to UV radiation (By similarity). Translocates from the nucleus to the cytoplasm into stress granules upon various cytoplasmic stresses, such as osmotic and heat shocks. Its recruitment into stress granules occurs in the absence of TIAR proteins.
Detection Range	0.156-10ng/mL
Entryname	CIRBP_MOUSE
Method Type	Sandwich
Platform	PF00076
Protein Name	Cold-inducible RNA-binding protein
Sensitivity	0.08ng/mL
Sequence	50: MASDEGKLFV ; GGLSFDTNEQ ; ALEQVFSKYG ; QISEVVVVKD ; RETQRSRGFG ; 100: FVTFENIDDA ; KDAMMAMNGK ; SVDGRQIRVD ; QAGKSSDNRS ; RGYRGGSAGG ; 150: RGFFRGGRSR ; GRGFSRGGGD ; RGYGGGRFES ; RSGGYGGSRD ; YYASRSQGGS ; 172: YGYRSSGGSY ; RDSYDSYATH ; NE
Sequence Length	172
String	P60824
Sub Unit	Interacts with EIF4G1. Associates with ribosomes.

Uniprot	P60824
Gene Name	Cirbp
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:12696
Unigene	Mm.17898

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SKU	Supplier No.	Size	Your price	Quantity
BHE13802085	E12931m	96T	$776		Add to Cart

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