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Home / Assay Kits / ELISA Kits

ELISA Kit for Human TNF receptor-associated factor 4

SKU : BHE13811460

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E15310h
Alternative Names	Cysteine-rich domain associated with RING and Traf domains protein 1 ; Metastatic lymph node gene 62 protein ; MLN 62 ; RING finger protein 83 ; CART1 ; MLN62 ; RNF83
Categories	Elisa
Function	Adapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. Plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis. Regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. Required for normal skeleton development, and for normal development of the respiratory tract (By similarity). Required for activation of RPS6KB1 in response to TNF signaling. Modulates TRAF6 functions.
Specificity	Natural and recombinant Human TNF receptor-associated factor 4
Subcellular Location	Cytoplasm Nucleus Cytoplasm perinuclear region Cell junction tight junction Cell membrane Peripheral membrane protein Cytoplasmic side Cytoplasm cytoskeleton
Entryname	TRAF4_HUMAN
Platform	PF00917
Protein Name	TNF receptor-associated factor 4
Sequence	50: MPGFDYKFLE ; KPKRRLLCPL ; CGKPMREPVQ ; VSTCGHRFCD ; TCLQEFLSEG ; 100: VFKCPEDQLP ; LDYAKIYPDP ; ELEVQVLGLP ; IRCIHSEEGC ; RWSGPLRHLQ ; 150: GHLNTCSFNV ; IPCPNRCPMK ; LSRRDLPAHL ; QHDCPKRRLK ; CEFCGCDFSG ; 200: EAYESHEGMC ; PQESVYCENK ; CGARMMRRLL ; AQHATSECPK ; RTQPCTYCTK ; 250: EFVFDTIQSH ; QYQCPRLPVA ; CPNQCGVGTV ; AREDLPGHLK ; DSCNTALVLC ; 300: PFKDSGCKHR ; CPKLAMARHV ; EESVKPHLAM ; MCALVSRQRQ ; ELQELRRELE ; 350: ELSVGSDGVL ; IWKIGSYGRR ; LQEAKAKPNL ; ECFSPAFYTH ; KYGYKLQVSA ; 400: FLNGNGSGEG ; THLSLYIRVL ; PGAFDNLLEW ; PFARRVTFSL ; LDQSDPGLAK ; 450: PQHVTETFHP ; DPNWKNFQKP ; GTWRGSLDES ; SLGFGYPKFI ; SHQDIRKRNY ; 470: VRDDAVFIRA ; AVELPRKILS ;
Sequence Length	470
String	Q9BUZ4
Sub Unit	Homotrimer (Probable). Interacts with LTBR/TNFRSF3, NGFR/TNFRSF16, RPS6KB1 and TGFB1I1. Interacts with SMURF1. Interacts (via TRAF domain) with MAP3K4 (via kinase domain). Interacts with NCF1, TICAM1, IRAK1 and TRAF6, and is probably part of a complex containing TRAF4, NCF1, TICAM1, IRAK1 and TRAF6.

Uniprot	Q9BUZ4
Gene Name	TRAF4
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:9618
Unigene	Hs.8375

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811460	E15310h	96T	$736		Add to Cart

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