ELISA Kit for Dog Intercellular adhesion molecule 1

Mfr.No.	E0048d
Alternative Names	CD54
Categories	Elisa
Function	ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.
Specificity	Natural and recombinant Dog Intercellular adhesion molecule 1
Subcellular Location	Membrane Single-pass type I membrane protein
Detection Range	0.78-50ng/mL
Entryname	ICAM1_CANFA
Method Type	Sandwich
Platform	PF03921
Protein Name	Intercellular adhesion molecule 1
Sensitivity	0.22ng/mL
Sequence	50: APALPRLPAL ; LALLGALLPG ; LGGAQTSVDP ; AEAIILRGGS ; VQVNCSTSCN ; 100: QTSIFGLETL ; LTKTEVTSGD ; NWVLFELTDV ; QEDSKLICFS ; NCHDETMAPI ; 150: DLTVYWFPER ; VELAPLPRWQ ; PVGENLTMTC ; QVAGGAPRTN ; LTVVLLRGEE ; 200: ELSRQPAVGE ; PAEVTFTVAV ; GREDHLANFS ; CRTDLDLRHR ; GLGLFQNSSA ; 250: PRQLQTFVLP ; ETPPRLATPP ; IVEVGTQWSV ; DCTMDGVFPA ; SEAQVHLALA ; 300: EERLHSTVLY ; KKDSLLATAN ; VKANPEDEGT ; QQLWCEVTLG ; DENRRWQENV ; 350: TFYSFPAPNL ; TLSEPEVSEW ; TTVTVECEAP ; AGVVVSLSGL ; PSGLAVPRAQ ; 400: FQLNASAADN ; RRSFSCSAAL ; EVAGHMLQKN ; QTRELHVLYG ; PRLDQRDCPG ; 450: NWTWEEGFHQ ; TLKCQAWGNP ; VPELKCHRKG ; DDALLPIGDL ; RPVKREVAGT ; 500: YLCQARSPRG ; EITREVVINV ; IYHQNNILII ; ILVTTIVILG ; TVSVAAYLYN ; 528: RQRKIQKYKL ; QKAQEAAAMK ; LNTPATPP
Sequence Length	528
Sub Unit	Homodimer. Interacts with MUC1 and promotes cell aggregation in epithelial cells. Interacts with ARHGEF26/SGEF.

Reference	1. "Cloning and comparative sequence analysis of the gene encoding canine intercellular adhesion molecule-1 (ICAM-1)." Manning A.M., Lu H.F., Kukielka G.L., Oliver M.G., Ty T., Toman C.A., Drong R.F., Slightom J.L., Ballantyne C.M., Entman M.L. Gene156:291-295(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 2. "Adherence of neutrophils to canine cardiac myocytes in vitro is dependent on intercellular adhesion molecule-1." Smith C.W., Entman M.L., Lane C.L., Beaudet A.L., Ty T.I., Youker K., Hawkins H.K., Anderson D.C. J. Clin. Invest.88:1216-1223(1991) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 184-413 tissue: Cardiac myocyte.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805419	E0048d	96T	$900		Add to Cart