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ELISA Kit for Dog Aggrecan core protein

SKU : BHE13808388

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1908d
Alternative Names	Cartilage-specific proteoglycan core protein ; CSPCP ; AGC1
Categories	Elisa
Function	This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.
Specificity	Natural and recombinant Dog Aggrecan core protein
Subcellular Location	Secreted extracellular space extracellular matrix
Detection Range	0.312-20ng/mL
Entryname	PGCA_CANFA
Method Type	Sandwich
Platform	PF00008
Protein Name	Aggrecan core protein
Sensitivity	0.079ng/mL
Sequence	50: MTTLLWVFVT ; LRVITAASSE ; ETSDHDNSLS ; VSIPEPSPMR ; VLLGSSLTIP ; 100: CYFIDPMHPV ; TTAPSTAPLA ; PRIKWSRITK ; EKEVVLLVAT ; EGQVRINSAY ; 150: QDKVSLPNYP ; AIPSDATLEI ; QNLRSNDSGI ; YRCEVMHGIE ; DSEATLEVVV ; 200: KGIVFHYRAI ; STRYTLDFDR ; AQRACLQNSA ; IIATPEQLQA ; AYEDGFHQCD ; 250: AGWLADQTVR ; YPIHTPREGC ; YGDKDEFPGV ; RTYGIRDTNE ; TYDVYCFAEE ; 300: MEGEVLYATS ; PEKFTFQEAA ; NECRRLGARL ; ATTGQLYLAW ; QGGMDMCSAG ; 350: WLADRSVRYP ; ISKARPNCGG ; NLLGVRTVYL ; HANQTGYPDP ; SSRYDAICYT ; 400: GEDFVDIPEN ; FFGVGGEEDI ; TIQTVTWPDV ; ELPLPRNITE ; GEARGNVILT ; 450: VKPIFDLSPT ; APEPEEPFTF ; VPEPEKPFTF ; ATDVGVTAFP ; EAENRTGEAT ; 500: RPWGVPEEST ; PGPAFTAFTS ; EDHVVQVTAV ; PGAAEVPGQP ; RLPGGVVFHY ; 550: RPGSARYSLT ; FEEAQQACLR ; TGAVIASPEQ ; LQAAYEAGYE ; QCDAGWLQDQ ; 600: TVRYPIVSPR ; TPCVGDKDSS ; PGVRTYGVRP ; PSETYDVYCY ; VDKLEGEVFF ; 650: ITRLEQFTFQ ; EALAFCESHN ; ATLASTGQLY ; AAWRQGLDKC ; YAGWLSDGSL ; 700: RYPIVTPRPS ; CGGDKPGVRT ; VYLYPNQTGL ; PDPLSRHHVF ; CFRGVSGVPS ; 750: PGEEEGGTPT ; PSVVEDWIPT ; QVGPVVPSVP ; MGEETTAILD ; FTIEPENQTE ; 800: WEPAYSPAGT ; SPLPGIPPTW ; PPTSTATEES ; TEGPSGTEVP ; SVSEEPSPSE ; 850: EPFPWEELST ; LSPPGPSGTE ; LPGSGEASGV ; PEVSGDFTGS ; GEVSGHPDSS ; 900: GQLSGESASG ; LPSEDLDSSG ; LTSAVGSGLA ; SGDEDRITLS ; SIPKVEGEGL ; 950: ETSASGVEDL ; SGLPSGREGL ; ETSTSGVGDL ; SGLPSGEGLE ; VSASGVEDLS ; 1000: GLPSGEGPET ; STSGVGDLSR ; LPSGEGPEVS ; ASGVGDLSGL ; PSGREGLETS ; 1050: TSGVEDLSGL ; PSGEGPEAST ; SGVGDLSRLP ; SGEGPEVSAS ; GVEDLSGLPS ; 1100: GEGLEASASG ; VGDLSGLPSG ; EGPEASASGV ; GDLSRLPSGE ; GPEVSASGVE ; 1150: DLSGLSSGES ; PEASASGVGD ; LSGLPSGREG ; LETSASGVGD ; LSGLPSGEGQ ; 1200: EASASGVEDL ; SRLPSGEGPE ; ASASGVGELS ; GLPSGREGLE ; TSASGVGDLS ; 1250: GLPSGEGPEA ; FASGVEDLSI ; LPSGEGPEAS ; ASGVGDLSGL ; PSGREGLETS ; 1300: TSGVGDLSGL ; PSGREGLETS ; TSGVGDLSGL ; PSGEGPEASA ; SGIGDISGLP ; 1350: SGREGLETSS ; SGVEDHPETS ; ASGVEDLSGL ; PSGVEGHPET ; SASGVEDLSD ; 1400: LSSGGEGLET ; SASGAEDLSG ; FPSGKEDLIG ; SASGALDFGR ; IPSGTLGSGQ ; 1450: APEASSLPSG ; FSGEYSGVDF ; GSGPISGLPD ; FSGLPSGFPT ; ISLVDTTLVE ; 1500: VITTTSASEL ; EGRGTIGISG ; AGETSGLPVS ; ELDISGAVSG ; LPSGAELSGQ ; 1550: ASGSPDMSGE ; TSGFFGVSGQ ; PSGFPDISGG ; TSGLFEVSGQ ; PSGFSGETSG ; 1600: VTELSGLYSG ; QPDVSGEASG ; VPSGSGQPFG ; MTDLSGETSG ; VPDISGQPSG ; 1650: LPEFSGTTSG ; IPDLVSSTMS ; GSGESSGITF ; VDTSLVEVTP ; TTFKEKKRLG ; 1700: SVELSGLPSG ; EVDLSGASGT ; MDISGQSSGA ; TDSSGLTSHL ; PKFSGLPSGA ; 1750: AEVSGESSGA ; EVGSSLPSGT ; YEGSGNFHPA ; FPTVFLVDRT ; LVESVTQAPT ; 1800: AQEAGEGPSG ; ILELSGAHSG ; APDVSGDHSG ; SLDLSGMQSG ; LVEPSGEPSS ; 1850: TPYFSGDFSG ; TMDVTGEPST ; AMSASGEASG ; LLEVTLITSE ; FVEGVTEPTV ; 1900: SQELAQRPPV ; THTPQLFESS ; GEASASGEIS ; GATPAFPGSG ; LEASSVPESS ; 1950: SETSDFPERA ; VGVSAAPEAS ; GGASGAPDVS ; EATSTFPEAD ; VEGASGLGVS ; 2000: GGTSAFPEAP ; REGSATPEVQ ; EEPTTSYDVG ; REALGWPSAT ; PTASGDRIEV ; 2050: SGDLSGHTSG ; LDVVISTSVP ; ESEWIQQTQR ; PAEAHLEIEA ; SSPLHSGEET ; 2100: QTAETATSPT ; DDASIPTSPS ; GTDESAPAIP ; DIDECLSSPC ; LNGATCVDAI ; 2150: DSFTCLCLPS ; YRGDLCEIDQ ; ELCEEGWTKF ; QGHCYRYFPD ; RESWVDAESR ; 2200: CRAQQSHLSS ; IVTPEEQEFV ; NNNAQDYQWI ; GLNDRTIEGD ; FRWSDGHSLQ ; 2250: FENWRPNQPD ; NFFVSGEDCV ; VMIWHEKGEW ; NDVPCNYYLP ; FTCKKGTVAC ; 2300: GDPPVVEHAR ; TFGQKKDRYE ; INSLVRYQCT ; EGFVQRHVPT ; IRCQPSGHWE ; 2333: KPRITCTDPS ; TYKRRLQKRS ; SRAPRRSRPS ; TAH
Sequence Length	2333
String	Q28343
Sub Unit	Interacts with FBLN1 and COMP.

Uniprot	Q28343
Gene Name	ACAN
Immunogen Species	Canis Lupus Familiaris (Dog)
Kegg	cfa:403828
Unigene	Cfa.3605

Reference	1. "Complete coding sequence and deduced amino acid sequence of aggrecan of canine cartilage." Glant T.T., Adams M.E., Kwok S.X.F., Huang D., Fueloep C. Submitted (2000-04) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 2. "Length variation in the keratan sulfate domain of mammalian aggrecan." Barry F.P., Neame P.J., Sasse J., Pearson D. Matrix Biol.14:323-328(1994) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 774-833 tissue: Cartilage. 3. Adams M.E., Kowk S.X.F., Huang D., Glant T.T., Fullop C. Submitted (1996-08) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1830-2333 4. "Expression of alternatively spliced epidermal growth factor-like domains in aggrecans of different species. Evidence for a novel module." Fueloep C., Walcz E., Valyon M., Glant T.T. J. Biol. Chem.268:17377-17383(1993) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2082-2118 tissue: Cartilage.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13808388	E1908d	96T	$900		Add to Cart

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