ELISA Kit for Bovine Insulin-like growth factor-binding protein 2

Mfr.No.	E0053b
Categories	Elisa
Function	Inhibits IGF-mediated growth and developmental rates (By similarity). IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Specificity	Natural and recombinant Bovine Insulin-like growth factor-binding protein 2
Subcellular Location	Secreted
Detection Range	0.312-20ng/mL
Entryname	IBP2_BOVIN
Method Type	Sandwich
Platform	PF00219
Protein Name	Insulin-like growth factor-binding protein 2
Sensitivity	0.082ng/mL
Sequence	50: MQPRLGGPAL ; LLLPPLLLLL ; LLGAGGGDCG ; ARAEVLFRCP ; PCTPESLAAC ; 100: KPPPGAAAGP ; AGDARVPCEL ; VREPGCGCCS ; VCARLEGERC ; GVYTPRCGQG ; 150: LRCYPNPGSE ; LPLRALVHGE ; GTCEKHGDAE ; YSASPEQVAD ; NGEEHSEGGL ; 200: VENHVDGNVN ; LMGGGGGAGR ; KPLKSGMKEL ; AVFREKVTEQ ; HRQMGKGGKH ; 250: HLGLEEPKKL ; RPPPARTPCQ ; QELDQVLERI ; STMRLPDERG ; PLEHLYSLHI ; 300: PNCDKHGLYN ; LKQCKMSLNG ; QRGECWCVNP ; NTGKLIQGAP ; TIRGDPECHL ; 317: FYNEQQGARG ; VHTQRMQ
Sequence Length	317
String	P13384
Sub Unit	Binds IGF2 more than IGF1.

Reference	1. "Cloning and sequence determination of bovine insulin-like growth factor binding protein-2 (IGFBP-2): comparison of its structural and functional properties with IGFBP-1." Bourner M.J., Busby W.H. Jr., Siegel N.R., Krivi G.G., McCusker R.H., Clemmons D.R. J. Cell. Biochem.48:215-226(1992) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];CHARACTERIZATION 2. "Characterization and cloning of a bovine insulin-like growth factor-binding protein." Upton F.Z., Szabo L., Wallace J.C., Ballard F.J. J. Mol. Endocrinol.5:77-84(1990) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 8-317 3. "The bovine insulin-like growth factor (IGF) binding protein purified from conditioned medium requires the N-terminal tripeptide in IGF-1 for binding." Szabo L., Mottershead D.G., Ballard F.J., Wallace J.C. Biochem. Biophys. Res. Commun.151:207-214(1988) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 34-86

Have you used this product?

SKU	Supplier No.	Size	Your price	Quantity
BHE13805418	E0053b	96T	$900		Add to Cart