ELISA Kit for Bovine Histone deacetylase 8

Mfr.No.	E1111b
Categories	Elisa
Function	Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). May play a role in smooth muscle cell contractility.
Specificity	Natural and recombinant Bovine Histone deacetylase 8
Subcellular Location	Nucleus Cytoplasm
Entryname	HDAC8_BOVIN
Platform	PF00850
Protein Name	Histone deacetylase 8
Sequence	50: MEESEEPADA ; GQSLPPVYIY ; SPEYVSVCDS ; LAKVPKRASM ; VHSLIEAYAL ; 100: HKQMRIVKPK ; VASMEEMASF ; HTDAYLQHLQ ; KVSEDGDDDH ; PDSIEYGLGY ; 150: DCPATEGIFD ; YAAAVGGATI ; TAAQCLIDGM ; CKVAINWSGG ; WHHAKKDEAS ; 200: GFCYLNDAVL ; GILRLRRKFD ; RILYVDLDLH ; HGDGVEDAFS ; FTSKVMTVSL ; 250: HKFSPGFFPG ; TGDVSDVGLG ; KGRYYSVNVP ; IQDCIQDERY ; YHICESVLKE ; 300: VYIAFNPKAV ; VLQLGADTIA ; GDPMCSFNMT ; PVGIGKCLKY ; ILQWELATLI ; 350: LGGGGYNLAN ; TARCWTYLTG ; VILGKTLSSE ; IPDHEFFTAY ; GPDYVLEITP ; 377: SCRPDRNEPH ; RVQQILNYIK ; GNLKHVV
Sequence Length	377
Sub Unit	Interacts with CBFA2T3 (By similarity). Interacts with phosphorylated SMG5/EST1B; this interaction protects SMG5 from ubiquitin-mediated degradation. Associates with alpha-SMA (smooth muscle alpha-actin).

Reference	1. NIH - Mammalian Gene Collection (MGC) project Submitted (2006-08) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: Hereford. tissue: Thymus.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805441	E1111b	96T	$900		Add to Cart