Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH(PubMed:2722838, PubMed:6894153). Involved in cellular response to oxidative stress(PubMed:25865492).
Categories
Primary Antibodies
Clonality
polyclonal
Description
Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH (PubMed:2722838, PubMed:6894153). Involved in cellular response to oxidative stress (PubMed:25865492).
Host
Rabbit
Immunogen
pyrroline-5-carboxylate reductase family, member 2
Isotype
IgG
Molecular Weight
34 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
P5C reductase 2, P5CR 2, P5CR2, PYCR2
Uniprot
Q96C36
Gene Id
29920
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)