This is a calcium-activated, phospholipid-dependent, serine- and threonine-specific enzyme. May play a role in cell motility by phosphorylating CSPG4. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
Formulation
Antibody in PBS with 50% Glycerol and 0.03% ProClin 300
Host
Mouse
Immunogen Region
A synthetic PKC alpha/aPKC peptide was used as the immunogen for the PKC alpha antibody.