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Home / Primary Antibodies / Polyclonal Antibodies

PKC epsilon antibody

SKU : BHA10806476

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Mfr.No.	FNab06484
Background	Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior.
Categories	Primary Antibodies
Clonality	polyclonal
Host	Rabbit
Immunogen	protein kinase C, epsilon
Isotype	IgG
Molecular Weight	90kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	PKCE, nPKC-epsilon

Uniprot	Q02156
Gene Id	5581
Research Area	Immunology, Cardiovascular, Metabolism, Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IP
Description	ELISA ; WB ; IHC ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; ICC: 1:50 - 1:200

Manual	FNab06484.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806476	FNab06484	100ug	$240		Add to Cart

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