MUC16, also named as CA125, is thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. It is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller subunits being described by some investigators. The antibody recognizes the C-term of MUC16.
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
mucin 16, cell surface associated
Isotype
IgG
Molecular Weight
90-100 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
CA 125, CA125, FLJ14303, MUC 16, MUC16, Mucin 16
Uniprot
Q8WXI7
Gene Id
94025
Research Area
Cancer, Immunology
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)