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Home / Primary Antibodies / Polyclonal Antibodies

MMP1 antibody

SKU : BHA10805225

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Mfr.No.	FNab05233
Alternative Names	CLG
Background	This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity.
Host	Rabbit
Immunogen	matrix metallopeptidase 1 (interstitial collagenase)
Isotype	IgG
Molecular Weight	54 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	CLG, CLGN, Fibroblast collagenase, Interstitial collagenase, Matrix metalloproteinase 1, MMP 1, MMP1

Uniprot	P03956
Gene Id	4312
Research Area	Cancer, Cardiovascular, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IF, IP, FC, IHC
Description	ELISA ; WB ; IF ; IP ; FC ; IHC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab05233.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10805225	FNab05233	100ug	$260		Add to Cart

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