MEMO1 (mediator of cell motility 1) is a protein-coding gene. Diseases associated with MEMO1 include hepatitis c virus, and hepatitis c.
Categories
Primary Antibodies
Clonality
polyclonal
Description
May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration.
Host
Rabbit
Immunogen
mediator of cell motility 1
Isotype
IgG
Molecular Weight
34 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
C2orf4, MEMO, NS5ATP7
Uniprot
Q9Y316
Gene Id
51072
Research Area
Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)