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Home / Primary Antibodies / Polyclonal Antibodies

MEF2A antibody

SKU : BHA10805092

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Mfr.No.	FNab05100
Alternative Names	MEF2
Background	Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA(AT)(4)TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor-and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle- specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.
Host	Rabbit
Immunogen	myocyte enhancer factor 2A
Isotype	IgG
Molecular Weight	54kd
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	ADCAD1, mef2, RSRFC4, RSRFC9

Uniprot	Q02078
Gene Id	4205
Research Area	Developmental biology, Cardiovascular, Metabolism, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500 - 1:2000

Manual	FNab05100.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10805092	FNab05100	100ug	$260		Add to Cart

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