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Home / Antibodies

MAP3K8/COT Antibody

SKU : BHA12901280

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AFFINITY BIOSCIENCES LTD

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Mfr.No.	AF6298
Alternative Names	AURA2 ; c COT ; Cancer Osaka thyroid oncogene ; CCOT ; COT ; COT proto oncogene serine/threonine protein kinase ; EST ; ESTF ; Ewing sarcoma transformant ; FLJ10486 ; M3K8_HUMAN ; MAP3K 8 ; MAP3K8 ; MEKK8 ; Mitogen activated protein kinase kinase kinase 8 ; Mitogen-activated protein kinase kinase kinase 8 ; Proto oncogene cCot ; Proto-oncogene c-Cot ; Serine/threonine protein kinase cot ; Serine/threonine-protein kinase cot ; TPL 2 ; TPL-2 ; TPL2 ; Tumor progression locus 2 ;
Categories	Primary Antibodies
Clonality	polyclonal
Description	This gene was identified by its oncogenic transforming activity in cells. The encoded protein is a member of the serine/threonine protein kinase family. This kinase can activate both the MAP kinase and JNK kinase pathways.
Immunogen	A synthesized peptide derived from human COT.
Molecular Weight	Observed Mol.Wt.: 60kDa. Predicted Mol.Wt.: 53kDa.
Reactivity	Human, Mouse, Rat
Specificity	COT Antibody detects endogenous levels of total COT.
Subcellular Location	Cytoplasm.

Uniprot

P41279

Gene Id

1326

Sequence

10	20	30	40	50
MEYMSTGSDN	KEEIDLLIKH	LNVSDVIDIM	ENLYASEEPA	VYEPSLMTMC
60	70	80	90	100
QDSNQNDERS	KSLLLSGQEV	PWLSSVRYGT	VEDLLAFANH	ISNTAKHFYG
110	120	130	140	150
QRPQESGILL	NMVITPQNGR	YQIDSDVLLI	PWKLTYRNIG	SDFIPRGAFG
160	170	180	190	200
KVYLAQDIKT	KKRMACKLIP	VDQFKPSDVE	IQACFRHENI	AELYGAVLWG
210	220	230	240	250
ETVHLFMEAG	EGGSVLEKLE	SCGPMREFEI	IWVTKHVLKG	LDFLHSKKVI
260	270	280	290	300
HHDIKPSNIV	FMSTKAVLVD	FGLSVQMTED	VYFPKDLRGT	EIYMSPEVIL
310	320	330	340	350
CRGHSTKADI	YSLGATLIHM	QTGTPPWVKR	YPRSAYPSYL	YIIHKQAPPL
360	370	380	390	400
EDIADDCSPG	MRELIEASLE	RNPNHRPRAA	DLLKHEALNP	PREDQPRCQS
410	420	430	440	450
LDSALLERKR	LLSRKELELP	ENIADSSCTG	STEESEMLKR	QRSLYIDLGA
460
LAGYFNLVRG	PPTLEYG

Concentration	1mg/ml
Format	Liquid
Purification	The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage Condition	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Applications	IF/ICC, ELISA, IHC, WB
Dilution	WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Manual
MSDS
IHC Protocol.
Western Blotting Handbook.

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SKU	Supplier No.	Size	Your price	Quantity
BHA12901280	AF6298	100ul	$280		Add to Cart
BHA12901280	AF6298	200ul	$350		Add to Cart

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