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Home / Primary Antibodies / Monoclonal Antibodies

liver Arginase antibody

SKU : BHA10804793

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Mfr.No.	FNab04801
Background	Arginase-1(Liver arginase) belongs to the arginase family. ARG1 is a novel immunohistochemical?marker?of hepatocellular differentiation in fine needle aspiration cytology and a marker?of hepatocytes and hepatocellular neoplasms. ARG1 is closely associated with alternative macrophage activation(PMID:12098359) and ARG1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia(ARGIN). Deletion or TNF-mediated restriction of ARG1 unleashes the production of NO by NOS2, which is critical for pathogen control.(PMID:27117406).
Categories	Primary Antibodies
Clonality	monoclonal
Host	Mouse
Immunogen	arginase, liver
Isotype	IgG2a
Molecular Weight	35 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	ARG1, Arginase 1, liver Arginase, Liver type arginase

Uniprot	P05089
Gene Id	383
Clone No	4A0
Research Area	Signal Transduction, Metabolism

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:1000-1:8000; IHC: 1:200-1:1000

Manual	FNab04801.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804793	FNab04801	100ug	$260		Add to Cart

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