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Home / Primary Antibodies

DCLK2 Antibody

SKU : BHA10557970

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA280806
Alternative Names	Serine/threonine-protein kinase DCLK2; EC 2.7.11.1; Doublecortin-like and CAM kinase-like 2; Doublecortin-like kinase 2; DCLK2
Categories	Primary Antibodies
Clonality	polyclonal
Description	Protein kinase with a significantly reduced C(a2+)/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm By similarity.Totoki Y., Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.Hillier L.W., Nature 434:724-731(2005).The German cDNA consortium, Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
Host	Rabbit
Immunogen	Synthesized peptide derived from internal of Human DCLK2.
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Protein kinase with a significantly reduced C(a2+)/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm By similarity. Totoki Y., Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases. Hillier L.W., Nature 434:724-731(2005). The German cDNA consortium, Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total DCLK2 protein.
Subcellular Location	Cytoplasm, cytoskeleton

Uniprot	Q8N568
Database Links	HGNC:19002 OMIM:613166 KEGG:hsa:166614 STRING:9606.ENSP00000303887 UniGene:Hs.591683
Function	Protein kinase with a significantly reduced C(a2+)/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm (By similarity).
Protein Families	Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily
Tissue Specificity	Expressed in the brain, heart and eyes.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:3000

Tested Application

ELISA,WB;WB:1:500-1:3000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10557970	CSB-PA280806	100ul	$297		Add to Cart

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