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Home / Primary Antibodies / Polyclonal Antibodies

DCK antibody

SKU : BHA10802259

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Mfr.No.	FNab02265
Background	Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). Has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. It is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents.
Host	Rabbit
Immunogen	deoxycytidine kinase
Isotype	IgG
Molecular Weight	30 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO

Uniprot	P27707
Gene Id	1633
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Manual	FNab02265.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802259	FNab02265	100ug	$240		Add to Cart

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