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Home / Primary Antibodies / Monoclonal Antibodies

CHOP; GADD153 antibody

SKU : BHA10801663

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Mfr.No.	FNab01668
Alternative Names	C/EBPhomologousprotein ; C/EBPhomologousprotein10 ; CEBPZ ; CHOP ; CHOP10 ; CHOP ; GADD153 ; CHOP10 ; DDIT3 ; DDIT3 ; GADD153
Background	CHOP, also known as GADD153 or DDIT3, is a highly conserved gene in both the structural and regulatory regions to hamster gene.Imposed by unfolded and malfolded proteins, CHOP is significantly induced by ER stress, deficiency of CHOP prevents cell from ER stress. CHOP is considered a proapoptotic marker of ER stress dependent cell death. CHOP acts as a dominant-negative inhibitor of the transcription factor C/EBP and LAP by forming a heterodimer. It may play an important role in the malignant transformation of nevus to melanoma.
Categories	Primary Antibodies
Clonality	monoclonal
Description	CHOP, also known as GADD153 or DDIT3, is a highly conserved gene in both the structural and regulatory regions to hamster gene.Imposed by unfolded and malfolded proteins, CHOP is significantly induced by ER stress, deficiency of CHOP prevents cell from ER stress. CHOP is considered a proapoptotic marker of ER stress dependent cell death. CHOP acts as a dominant-negative inhibitor of the transcription factor C/EBP and LAP by forming a heterodimer. It may play an important role in the malignant transformation of nevus to melanoma.
Host	Mouse
Immunogen	DNA-damage-inducible transcript 3
Isotype	IgG2a
Molecular Weight	30 kDa
Reactivity	Human
Regulatory	RUO
Synonyms	C/EBP homologous protein, C/EBP homologous protein 10, CEBPZ, CHOP, CHOP 10, CHOP; GADD153, CHOP10, DDIT 3, DDIT3, GADD153

Uniprot	P35638
Clone No	5H7
Research Area	Epigenetics, Stem Cells, Metabolism
Weight	20kDa,observed 30kDa,40kDa

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB

Description

ELISA ; WB

Dilution

WB	1:500-1:5000

Tested Application

WB: 1:500-1:5000

Manual	FNab01668.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801663	FNab01668	100ug	$300		Add to Cart

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