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Home / Primary Antibodies / Polyclonal Antibodies

CEP164 antibody

SKU : BHA10801593

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Mfr.No.	FNab01598
Alternative Names	KIAA1052 ; NPHP15
Background	This gene encodes a centrosomal protein involved in microtubule organization, DNA damage response, and chromosome segregation. The encoded protein is required for assembly of primary cilia and localizes to mature centrioles. Defects in this gene are a cause of nephronophthisis-related ciliopathies. Two transcript variants encoding different isoforms have been found for this gene.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Plays a role in microtubule organization and/or maintenance for the formation of primary cilia (PC), a microtubule-based structure that protrudes from the surface of epithelial cells. Plays a critical role in G2/M checkpoint and nuclear divisions. A key player in the DNA damage-activated ATR/ATM signaling cascade since it is required for the proper phosphorylation of H2AX, RPA, CHEK2 and CHEK1. Plays a critical role in chromosome segregation, acting as a mediator required for the maintenance of genomic stability through modulation of MDC1, RPA and CHEK1.
Host	Rabbit
Immunogen	centrosomal protein 164kDa
Isotype	IgG
Molecular Weight	160 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	KIAA1052, NPHP15

Uniprot	Q9UPV0
Gene Id	22897
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IP, IF, IHC, WB
Description	ELISA ; IP ; IF ; IHC ; WB
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab01598.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801593	FNab01598	100ug	$240		Add to Cart

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