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Home / Primary Antibodies / Polyclonal Antibodies

CENPC antibody

SKU : BHA10801579

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Mfr.No.	FNab01584
Alternative Names	CENPC1 ; ICEN7
Background	Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions.
Host	Rabbit
Immunogen	centromere protein C 1
Isotype	IgG
Molecular Weight	130 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	CENPC1, ICEN7

Uniprot	Q03188
Gene Id	1060
Research Area	Proliferation, Cell Division

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab01584.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801579	FNab01584	100ug	$260		Add to Cart

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