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Home / Primary Antibodies / Polyclonal Antibodies

BMP3 antibody

SKU : BHA10800913

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Mfr.No.	FNab00918
Alternative Names	BMP3A
Background	This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification.
Host	Rabbit
Immunogen	bone morphogenetic protein 3
Isotype	IgG
Molecular Weight	53 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	BMP3A

Uniprot	P12645
Gene Id	651
Research Area	Developmental biology, Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:100 - 1:200

Manual	FNab00918.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800913	FNab00918	100ug	$240		Add to Cart

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