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Home / Antibodies

Anti-Tet1 Antibody BHA11308977

SKU : BHA11308977

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Mfr.No.	BZ12161
Alternative Names	Methylcytosine dioxygenase TET1 ; CXXC-type zinc finger protein 6 ; Ten-eleven translocation 1 gene protein homolog ; Cxxc6 ; Kiaa1676
Categories	Primary Antibodies
Clonality	polyclonal
Description	Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5- hydroxymethylcytosine (5hmC) and plays a key role in active DNA demethylation. Also mediates subsequent conversion of 5hmC into 5- formylcytosine (5fC), and conversion of 5fC to 5-carboxylcytosine (5caC). Conversion of 5mC into 5hmC, 5fC and 5caC probably constitutes the first step in cytosine demethylation. Methylation at the C5 position of cytosine bases is an epigenetic modification of the mammalian genome which plays an important role in transcriptional regulation.
Host	Rabbit
Immunogen	This mouse Tet1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1845-1879 amino acids from the C-terminal region of mouse Tet1.
Reactivity	Mouse
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q3URK3
Uniprot	Q3URK3
Weight	219 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: Tet1 (C-term) polyclonal antibody detects endogenous levels of Tet1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB

1:2000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11308977	BZ12161	50µl	$270.44		Add to Cart
BHA11308977	BZ12161	100µl	$403.78		Add to Cart

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