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Home / Primary Antibodies / IHC Antibodies

Anti-SYT2/SYT1 Antibody BHA11302472

SKU : BHA11302472

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Mfr.No.	BS4191
Alternative Names	Synaptotagmin-1 ; Synaptotagmin 1 ; Synaptotagmin I ; SytI ; SYT1 ; SVP65 ; SYT ; Synaptotagmin-2 ; Synaptotagmin 2 ; Synaptotagmin II ; SytII ; SYT2
Antigen	SYT2/SYT1
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	Synaptotagmins are a large gene family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles. Calcium binds to Synaptotagmin I which triggers neurotransmitter release at the synapse. Synaptotagmin II is phosphorylated by WNK1 in a process that regulates calcium-dependent interactions. Synaptotagmin III is involved in calcium-dependent exocytosis of secretory vesicles in endocrine cells and neurons. Synaptotagmin IV is expressed in neuronal tissues, and has the highest mRNA levels in the hippocampus.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human Synaptotagmin 1 around the phosphorylation site of Threonine 202.
Modification	phospho-T202/199
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P21579/Q8N9I0
Uniprot	P21579/Q8N9I0
Weight	60 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: p-Synaptotagmin 1/2 (T202/199) polyclonal antibody detects endogenous levels of Synaptotagmin 1/2 protein only when phosphorylated at SerT202/199.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302472	BS4191	50µl	$199.33		Add to Cart
BHA11302472	BS4191	100µl	$314.89		Add to Cart

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