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Home / Primary Antibodies / Recombinant Antibodies

Anti-STAT5B Antibody BHA11303458

SKU : BHA11303458

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Mfr.No.	BS6031
Alternative Names	Signal transducer and activator of transcription 5B ; STA5B ; STAT5 ; Stat5b ; Transcription factor STAT5B
Antigen	STAT5b
Categories	Primary Antibodies
Clonality	polyclonal
Description	Stat5a and Stat5b (signal transducer and activator of transcription 5a and 5b; 96% homology) undergo receptor tyrosine kinase or G protein-coupled receptor-dependent phosphorylation in response to cytokines or growth factors, and then form homo- or heterodimers that translocate to the nucleus where they initiate transcription. Activation of Stat5b via IL-2, IL-4, CSF1 and growth hormones influences TCR signaling, apoptosis, adult mammary gland development and sexual dimorphism of liver gene expression. Stat5b is the major liver-expressed Stat5 form that has been shown to fuse with retinoic acid receptor-α gene in acute promyelocytic leukemias (APLL).
Host	Rabbit
Immunogen	Recombinant full length Human Stat5b.
Reactivity	Human, Rat
Recombinant	TRUE
Regulatory	RUO

Swissprot	P51692
Uniprot	P51692
Weight	90 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: STAT5B polyclonal antibody detects endogenous levels of STAT5B protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IF

Description

WB ; IF

Dilution

WB	1:500-1:2000
IF	1:50-1:200

Datasheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA11303458	BS6031	50µl	$234.89		Add to Cart
BHA11303458	BS6031	100µl	$368.22		Add to Cart

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