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Home / Primary Antibodies / Recombinant Antibodies

Anti-SERPINA1 Antibody BHA11305164

SKU : BHA11305164

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Mfr.No.	BS6957
Alternative Names	Alpha-1-antitrypsin ; Alpha-1 protease inhibitor ; Alpha-1-antiproteinase ; Serpin A1 ; Short peptide from AAT ; SPAAT ; AAT ; PI ; ORF Names: PRO0684, PRO2209 ; α-1-antitrypsin ; α-1 protease inhibitor ; α-1-antiproteinase ; α1-antitrypsin ; α1 protease inhibitor ; α1-antiproteinase ; α1 antitrypsin ; α1 antiproteinase
Antigen	SERPINA1
Categories	Primary Antibodies
Chromosome Location	14q32.13
Clonality	polyclonal
Description	SERPINA1 is secreted and is a serine protease inhibitor which its targets include elastase, plasmin, collagenase, thrombin, leucocytic proteases, trypsin, chymotrypsin, and plasminogen activator. Defects in SERPINA1 gene can cause emphysema or liver disease. Antral SERPINA1 expression is particularly induced by H. pylori infection. lung and prostate cancers have shown a significant increase in SERPINA1 serum levels compared with healthy controls though breast cancers did not show a significant change. SERPINA1 is an endogenous inhibitor of serine proteases and inhibits the catalytic domain of human recombinant matriptase in vitro. Rise in SERPINA1 occurs as an acute phase response to tissue necrosis and inflammation. mutations in SERPINA1 and SLC11A1 genes change the balance between elastase produced by leukocytes during phagocytosis.
Host	Rabbit
Immunogen	Recombinant full length Human SERPINA1.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P01009
Uniprot	P01009
Weight	46, 55 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: SERPINA1 polyclonal antibody detects endogenous levels of SERPINA1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF

Description

WB ; IHC ; IF

Dilution

WB	1:500-1:2000
IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11305164	BS6957	50µl	$234.89		Add to Cart
BHA11305164	BS6957	100µl	$368.22		Add to Cart

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