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Home / Primary Antibodies / Recombinant Antibodies

Anti-RNASEL Antibody BHA11306147

SKU : BHA11306147

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Mfr.No.	BS71344
Alternative Names	2-5A-dependent Rnase ; Ribonuclease 4 ; Ribonuclease L ; RNase L ; RNASEL ; RNS4
Antigen	RNASEL
Categories	Primary Antibodies
Chromosome Location	1q25.3
Clonality	polyclonal
Description	RNase L encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele. Interferon treatment enhances levels of both RNase L and a group of synthetases that produce 5-prime-triphosphorylated, 2-prime,5-prime-oligoadenylates (2-5A) from ATP. The role of the 2-5A system in the control of viral and cellular growth suggests that defects in the 2-5A-dependent RNase gene could result in reduced immunity to viral infections and cancer.
Host	Rabbit
Immunogen	Recombinant protein of human RNASEL.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q05823
Uniprot	Q05823
Weight	84 kDa

Description	Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Specificity: RNase L polyclonal antibody detects endogenous levels of RNase L protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:2000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11306147	BS71344	50µl	$234.89		Add to Cart
BHA11306147	BS71344	100µl	$368.22		Add to Cart

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