Anti-PTK2 Antibody BHA11308881

Mfr.No.	BS9850M
Alternative Names	Focal adhesion kinase 1 ; FADK 1 ; Focal adhesion kinase-related nonkinase ; FRNK ; Protein phosphatase 1 regulatory subunit 71 ; PPP1R71 ; Protein-tyrosine kinase 2 ; p125FAK ; pp125FAK ; PTK2 ; FAK ; FAK1
Antigen	PTK2
Categories	Primary Antibodies
Chromosome Location	8q24.3
Clonality	monoclonal
Description	Focal adhesion kinase was initially identified as a major 125 kDa substrate for the intrinsic protein tyrosine kinase activity of Src-encoded pp60. The deduced amino acid sequence of FAK p125 has shown it to be a cytoplasmic protein tyrosine kinase whose sequence and structural organization are unique as compared to other proteins described to date. Localization of p125 by immunofluorescence suggests that it is primarily found in cellular focal adhesions leading to its designation as focal adhesion kinase (FAK). FAK is concentrated at the basal edge of only basal keratinocytes that are actively migrating and rapidly proliferating in repairing burn wounds, and is activated and localized to the focal adhesions of spreading keratinocytes in culture.
Host	Rabbit
Immunogen	Recombinant antibody.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Description	Product: Recombinant Rabbit Monoclonal Antibody. 1TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. Specificity:* This antibody detects endogenous levels of FAK and does not cross-react with related proteins.
Purity	Protein A affinity purified
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.