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Home / Primary Antibodies / Recombinant Antibodies

Anti-PNOC Antibody BHA11308092

SKU : BHA11308092

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Mfr.No.	BS8183
Alternative Names	Prepronociceptin ; PNOC ; OFQ
Antigen	PNOC
Categories	Primary Antibodies
Chromosome Location	8p21.1
Clonality	polyclonal
Description	Nociception, a pain response mechanism, occurs in response to stimuli that threaten the integrity of an organism. The first synapses produced as a result of the initiation of nociception are modulated by excitatory amino acids (glutamate and aspartate) and many peptides (substance P, CGRP, CCK, endogenous opioids). Nociceptin (also designated orphanin FQ) is a neuronal peptide that is similar to opioid peptides. Nociceptin activates KOR-3 (kappa-type opioid receptor, also designated ORL1), a G protein-coupled receptor. Although similar to dynorphin A, a kappa opioid peptide, nociceptin functions to make animals hyperreactive to nociceptive stimulations. Nociceptin is also involved in locomotor behavior and may be involved in the modulation of synaptic plasticity in learning and memory.
Host	Rabbit
Immunogen	Recombinant full length Human PNOC.
Reactivity	Human
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q13519
Uniprot	Q13519
Weight	20 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: PNOC polyclonal antibody detects endogenous levels of PNOC protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IF

Description

WB ; IF

Dilution

WB	1:500-1:2000
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11308092	BS8183	50µl	$234.89		Add to Cart
BHA11308092	BS8183	100µl	$368.22		Add to Cart

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