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Home / Primary Antibodies / IHC Antibodies

Anti-NRAS/KRAS/HRAS Antibody BHA11300473

SKU : BHA11300473

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Mfr.No.	BS1309
Alternative Names	GTPase HRas ; H-Ras-1 ; Ha-Ras ; Transforming protein p21 ; c-H-ras ; p21ras ; HRAS ; HRAS1 ; GTPase NRas ; Transforming protein N-Ras ; NRAS ; HRAS1 ; GTPase KRas ; K-Ras 2 ; Ki-Ras ; c-K-ras ; c-Ki-ras ; GTPase KRas ; KRAS ; KRAS2, RASK2
Antigen	NRAS/KRAS/HRAS
Categories	Primary Antibodies
Clonality	polyclonal
Description	The KRAS gene encodes the human cellular homolog of a transforming gene isolated from the Kirsten rat sarcoma virus. The RAS proteins are GDP/GTP-binding proteins that act as intracellular signal transducers. The most well-studied members of the RAS (derived from 'RAt Sarcoma' virus) gene family include KRAS, HRAS, and NRAS. These genes encode immunologically related proteins with a molecular mass of 21 kD and are homologs of rodent sarcoma virus genes that have transforming abilities. While these wildtype cellular proteins in humans play a vital role in normal tissue signaling, including proliferation, differentiation, and senescence, mutated genes are potent oncogenes that play a role in many human cancers.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 1-50 of Human Ras.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	P01112/P01116/P01111
Uniprot	P01112/P01116/P01111
Weight	21 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: Ras (H27) polyclonal antibody detects endogenous levels of total K-Ras, H-Ras and N-Ras proteins.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300473	BS1309	50µl	$190.44		Add to Cart
BHA11300473	BS1309	100µl	$294.44		Add to Cart

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