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Home / Antibodies

Anti-MMP15 Antibody BHA11305281

SKU : BHA11305281

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Mfr.No.	BS7041
Alternative Names	Matrix metalloproteinase-15 ; MMP-15 ; Membrane-type matrix metalloproteinase 2 ; MT-MMP 2 ; MTMMP2 ; Membrane-type-2 matrix metalloproteinase ; MT2-MMP ; MT2MMP ; SMCP-2 ; MMP15
Antigen	MMP15
Categories	Primary Antibodies
Chromosome Location	16q21
Clonality	polyclonal
Description	The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-9 (also designated 92 kDa type IV collagenase or gelatinase B) has been shown to degrade bone collagens in concert with MMP-1 (also designated interstitial collagenase, fibroblast collagenase or collagenase-1), and cysteine proteases and may play a role in bone osteoclastic resorption. MMP-1 is downregulated by p53, and abnormality of p53 expression may contribute to joint degradation in rheumatoid arthritis by regulating MMP-1 expression.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 100-150 of Human MMP-15.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P51511
Uniprot	P51511
Weight	61, 80 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: Cleaved-MMP-15 (Y132) polyclonal antibody detects endogenous levels of Cleaved-MMP-15 (60 kDa) protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11305281	BS7041	50µl	$190.44		Add to Cart
BHA11305281	BS7041	100µl	$294.44		Add to Cart

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