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Home / Primary Antibodies / Recombinant Antibodies

Anti-CIAPIN1 Antibody BHA11308061

SKU : BHA11308061

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Mfr.No.	BS8142
Alternative Names	Anamorsin ; Cytokine-induced apoptosis inhibitor 1 ; Fe-S cluster assembly protein DRE2 homolog ; CIAPIN1 ; CUA001 ; PRO0915
Antigen	CIAPIN1
Categories	Primary Antibodies
Chromosome Location	16q21
Clonality	polyclonal
Description	The name of the protein Anamorsin, also designated cytokine-induced apoptosis inhibitor 1 (CIAPIN1), comes from the Latin term “ana-mors-in”, meaning “anti-death molecule”. During hematopoiesis, Anamorsin is crucial for mediating the anti-apoptotic effects of various cytokines. It is a ubiquitously expressed protein, and when it is overexpressed, it confers apoptotic resistance. Anamorsin is primarily expressed in the cytoplasm of liver, pancreas and heart tissue cells and does not show any homology to known apoptosis regulatory molecules of the Bcl-2 or CASP families, or to signal transduction molecules. Anamorsin expression in mouse cells confers resistance to apoptosis caused by IL-3 (interleukin-3) deprivation. Studies demonstrate that the addition of growth factors, such as EPO (erythropoietin), SCF (stem cell factor), TPO (thrombopoietin) or IL-3, all of which depend on RAS signaling, induce dose-dependent expression of Anamorsin in mouse cells.
Host	Rabbit
Immunogen	Recombinant full length Human CIAPIN1.
Reactivity	Human, Mouse
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q6FI81
Uniprot	Q6FI81
Weight	34 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: CIAPIN1 polyclonal antibody detects endogenous levels of CIAPIN1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF

Description

WB ; IHC ; IF

Dilution

WB	1:500-1:2000
IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11308061	BS8142	50µl	$234.89		Add to Cart
BHA11308061	BS8142	100µl	$368.22		Add to Cart

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