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Home / Primary Antibodies / Recombinant Antibodies

Anti-CHIA Antibody BHA11305151

SKU : BHA11305151

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Mfr.No.	BS6942
Alternative Names	Acidic mammalian chitinase ; AMCase ; Lung-specific protein TSA1902 ; CHIA
Antigen	CHIA
Categories	Primary Antibodies
Chromosome Location	1p13.2
Clonality	polyclonal
Description	Chitinases are ubiquitous chitin-fragmenting hydrolases. The chitinase Chitotriosidase is capable of cleaving natural chitin and chitin-like substrates in humans and may play a role in immunity against pathogens containing chitin. Activated human macrophages secrete chitotriosidase, and increased plasma levels of chitotriosidase are a feature of patients suffering from Gaucher’s disease. Expression of mouse Chitotriosidase is restricted to brain, skin, bone marrow, kidney, tongue, stomach and testis. The homology between chitotriosidase and chitinases found in lower organisms is significant. Acidic mammalian chitinase precursor (AMCase) degrades chitotriose and chitin. AMCase is highly expressed in stomach tissues and is primarily a secreted protein. It is involved in Th2-mediated inflammation and may play a role in asthma and allergic diseases.
Host	Rabbit
Immunogen	Recombinant full length Human CHIA.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q9BZP6
Uniprot	Q9BZP6
Weight	52 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: CHIA polyclonal antibody detects endogenous levels of CHIA protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:2000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11305151	BS6942	50µl	$234.89		Add to Cart
BHA11305151	BS6942	100µl	$368.22		Add to Cart

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