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Home / Primary Antibodies / Recombinant Antibodies

Anti-BIN1 Antibody BHA11307780

SKU : BHA11307780

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Mfr.No.	BS7684
Alternative Names	AMPH 2 ; AMPH2 ; Amphiphysin 2 ; Amphiphysin II ; Amphiphysin like protein ; amphiphysin-like ; Amphiphysin-like protein ; AMPHL ; Bin1 ; BIN1_HUMAN ; Box Dependant MYC Interacting Protein 1 ; Box-dependent myc-interacting protein 1 ; Bridging integrator 1 ; DKFZp547F068 ; MGC10367 ; MGC105358 ; Myc box dependent interacting protein 1 ; Myc box-dependent-interacting protein 1 ; SH3P9
Antigen	BIN1
Categories	Primary Antibodies
Chromosome Location	2q14.3
Clonality	polyclonal
Description	This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. [provided by RefSeq, Sep 2011]
Host	Rabbit
Immunogen	Recombinant full length Human BIN1.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	O00499
Uniprot	O00499
Weight	65 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: BIN1 polyclonal antibody detects endogenous levels of BIN1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF

Description

WB ; IHC ; IF

Dilution

WB	1:500-1:2000
IHC/IF	1:50-1:200

Datasheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA11307780	BS7684	50µl	$234.89		Add to Cart
BHA11307780	BS7684	100µl	$368.22		Add to Cart

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