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Home / Primary Antibodies / IHC Antibodies

Anti-CCNA2/CCNA1 Antibody BHA11300265

SKU : BHA11300265

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Mfr.No.	BS1083
Alternative Names	Cyclin-A1 ; CCNA1 ; Cyclin A1 ; CyclinA1 ; Cyclin-A2 ; Cyclin-A ; Cyclin A ; CyclinA ; CCNA2 ; CCN1 ; CCNA
Antigen	CCNA2/CCNA1
Categories	Primary Antibodies
Clonality	polyclonal
Description	The critical role that the family of regulatory proteins known as cyclins play in eukaryotic cell cycle regulation is well established. The best-characterized cyclin complex is the mitotic cyclin B/Cdc2 p34 kinase, the active component of maturing promoting factor. Cyclin A accumulates prior to cyclin B in the cell cycle, appears to be involved in control of S phase and has been shown to associate with cyclin-dependent kinase-2 (Cdk2). In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcription factors DRTF1 and E2F and retinoblastoma protein, p110. A second form of cyclin A, named cyclin A1 because of its high sequence homology to Xenopus cyclin A1, is most highly expressed in germ cells. It has been proposed that cyclin A1 can associate with Cdk2, p39 and Cdc2 p34.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 220-270 of Human Cyclin A.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	P78396/P20248
Uniprot	P78396/P20248
Weight	52 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: Cyclin A (W250) polyclonal antibody detects endogenous levels of Cyclin A protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF

Description

WB ; IHC ; IF

Dilution

WB	1:500-1:1000
IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300265	BS1083	50µl	$190.44		Add to Cart
BHA11300265	BS1083	100µl	$294.44		Add to Cart

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