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Anti-FGL2 Antibody BHA11301691
Alternative: Fibroleukin|Fibrinogen-like protein 2|pT49|FGL2
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: Primary Antibodies|Polyclonal Antibodies
Chromosome Location: 7q11.23
Immunogen: Synthetic peptide, corresponding to amino acids 6-60 of Human Fgl2.
Description: Fibrinogen-like protein 2 (Fgl2), also known as fibroleukin, is secreted by T cells and is involved in diseases in which thrombosis plays a pivotal role,such as virus-induced fulminant hepatitis, fetal loss syndrome and xenograft rejection. Constitutively xpressed in cytotoxic T cells, Fgl2 exerts immunosuppressive effects on both T cell proliferation and dendritic cell maturation.
Fgl2 is a serine protease and directly cleaves prothrombin to thrombin. Fgl2 functions in the pathogenesis of diseases including viral-induced hepatitis and Th1 cytokine-induced fetal loss syndrome.
TARGETWeight: 50 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Specificity: Fgl2 (V38) polyclonal antibody detects endogenous levels of Fgl2 protein.
Description: Western blot (WB) analysis of Fgl2 (V38) pAb at 1:500 dilutionLane1:CT26 whole cell lysate(40ug)Lane2:SP2/0 whole cell lysate(40ug)Lane3:C6 whole cell lysate(40ug)Lane4:A549 whole cell lysate(40ug)Lane5:Hela whole cell lysate(40ug)