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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hPD-L1(BALB/c,2)
- Nomenclature : BALB/cAnSmoc-Cd
- KI/KO Gene : Cd274
- Strain : Developing
- Description : Model Descripti
- Synonyms : B7h1, Pdl1, Pdc
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hSIRPA(BALB/c,2)
- Nomenclature : BALB/cAnSmoc-Si
- KI/KO Gene : Sirpa
- Research Application : Immunotherapy
- Strain : Embryo cryopres
- Target : Immune Checkpoi
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hSIRPA(BALB/c)
- Nomenclature : BALB/cAnSmoc-Si
- KI/KO Gene : Sirpa
- Research Application : Immunotherapy
- Strain : Developing
- Description : Model Descripti
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hTGFBR2(2)
- Nomenclature : C57BL/6JSmoc-Tg
- KI/KO Gene : Tgfbr2
- Strain : Developing
- Description : Model Descripti
- Synonyms : DNIIR, RIIDN, T
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hTIGIT/hCCR8
- Nomenclature : C57BL/6JSmoc-Ti
- KI/KO Gene : CCR8
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- Description : Model Descripti
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hTIGIT(3)/hTNFRSF1B
- Nomenclature : C57BL/6JSmoc-Ti
- KI/KO Gene : TIGIT
- Research Application : Immunotherapy
- Strain : Developing
- Description : Model Descripti
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hTLR9/hOX40
- Nomenclature : C57BL/6JSmoc-Tl
- KI/KO Gene : Tnfrsf4
- Research Application : Immune-related
- Strain : Embryo cryopres
- Target : Immune Checkpoi
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hTNFRSF12A
- Nomenclature : C57BL/6JSmoc-Tn
- KI/KO Gene : Tnfrsf12a
- Strain : Developing
- Description : Model Descripti
- Synonyms : Fn14, HPIP, C87
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hTNFRSF10B
- Nomenclature : C57BL/6JSmoc-Tn
- KI/KO Gene : Tnfrsf10b
- Research Application : Immunotherapy
- Strain : Embryo cryopres
- Target : Cytokine Recept
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hFCGR2B/h4-1BB(2)
- Strain : Embryo cryopres
- KI/KO Gene : Fcgr2b
- Nomenclature : C57BL/6Smoc-Fcg
- Research Application : Immunotherapy
- Description : hFCGR2B(NM-HU-2
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