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Home / VECTOR &VIRUS / Lentivirus

HOXA9 Reporter Lentivirus

SKU : BHV19400075

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Mfr.No.	LTV-0082, LTV-0082-1S, LTV-0082-2S, LTV-0082-3S, LTV-0082-4S, LTV-0082-5S, LTV-0082-6S
Promoter	EF1a
Serotype	VSV-G
Description	HOXA9 Reporter Lentivirus: High-quality, lentiviral transcription factor (TF) reporter system that provides a sensitive fluorescent or luminescent readout for human/mouse HOXA9 transcriptional activity in mammalian cells. The HOXA9 Reporter Lentivirus is constructed with tandem repeats of the consensus HOXA9 DNA-binding elements which is transcriptionally responsive to the transcription factor HOXA9. The HOXA9 reporter construct contains consensus MEIS1 DNA-binding motifs combined with HOXA9 DNA-binding elements. The cooperation between HOXA9 and MEIS1 induces acute myeloid leukemia through mechanisms in which they bind to the super-enhancer regions of genes involved in the growth and less differentiation of hematopoietic stem cells. The reporter lentivirus is purified by PEG precipitation and sucrose gradient centrifugation, and is ideal for studying HOXA9 transcriptional activity in difficult-to-transfect cells including primary and/or thawed cells.
Reporter	Firefly Luc, RFP, GFP
Response Element	HOXA9 response element
Selection	Blasticidin, Puromycin
Signaling pathway	HOXA9 Signaling Pathway
Species	Human/mouse
Applications Range	Monitor transcriptional activity of HOXA9 in mammalian cells, screen for activators or inhibitors of HOXA9 transcriptional activity. The fluorescent reporter enables convenient readout using flow cytometry, fluorescence microscopy, etc. The HOXA9 Reporter Lentivirus is constructed with tandem repeats of the consensus HOXA9 DNA-binding elements which is transcriptionally responsive to the transcription factor HOXA9. The lentiviral HOXA9 reporter is constructed with tandem repeats of the consensus HOXA9 DNA-binding element to measure HOXA9 transcriptional activity in mammalian cells. The HOXA9 reporter construct contains consensus MEIS1 DNA-binding motifs combined with HOXA9 DNA-binding elements. The cooperation between HOXA9 and MEIS1 induces acute myeloid leukemia through mechanisms in which they bind to the super-enhancer regions of genes involved in the growth and less differentiation of hematopoietic stem cells.
Virus Type	TF Reporter Lentivirus

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Combination SKU	Supplier No.	Amount (TU)	Selection	Reporter	Promoter	Your price	Quantity
BHV19400075-1	LTV-0082-1S	5x10^6	Puromycin	GFP	EF1a	$595		Add to Cart
BHV19400075-2	LTV-0082-2S	5x10^6	Blasticidin	RFP	EF1a	$595		Add to Cart
BHV19400075-3	LTV-0082-3S	2x10^6	Puromycin	Firefly Luc	EF1a	$595		Add to Cart
BHV19400075-4	LTV-0082-4S	2x10^6	Blasticidin	Firefly Luc	EF1a	$595		Add to Cart
BHV19400075-5	LTV-0082-5S	5x10^6	Blasticidin	GFP	EF1a	$595		Add to Cart
BHV19400075-6	LTV-0082-6S	5x10^6	Puromycin	RFP	EF1a	$595		Add to Cart

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