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Home / Primary Antibodies / Phospho Antibodies

Anti-ALK Antibody BHA11307580

SKU : BHA11307580

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Mfr.No.	BS74002
Alternative Names	CD246 ; NBLST3
Antigen	ALK
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	2p23.2-p23.1
Clonality	polyclonal
Description	This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), ALK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X).
Host	Rabbit
Immunogen	A phospho specific peptide corresponding to residues surrounding Y1096 of human ALK.
Modification	phospho-Y1096
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q9UM73
Uniprot	Q9UM73
Weight	176 kDa

Description	Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Specificity: ALK (phospho-Y1096) polyclonal antibody detects endogenous levels of ALK protein only when phosphorylated at Tyr1096.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:2000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11307580	BS74002	50µl	$252.67		Add to Cart
BHA11307580	BS74002	100µl	$403.78		Add to Cart

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